Reality of Sepsis



STAGES OF SEPSIS5

STAGE 1:
SIRS

Defined as two or more of the following variables:

  • Temperature > 38°C (100.4°F) or < 36°C (96.8°F)
  • Heart rate > 90 BPM
  • Respiratory rate > 20 breaths per minute, or PaCO2 < 32 mmHg; or
  • White blood cell count > 12,000/uL or < 4,000/uL or > 10% immature [band] forms

STAGE 2:
SEPSIS

  • Two or more SIRS criteria + a confirmed infection
  • Patient demonstrates positive blood and urine cultures and positive
    diagnostic imaging

STAGE 3:
SEVERE
SEPSIS

Diagnosis of sepsis + beginnings of:

  • Multiorgan failure or disfunction
  • Hypoperfusion
  • Hypotension

Systemic symptoms such as:

  • Hypoxia
  • Oliguria (i.e., decreased urine output)
  • Lactic acidosis
  • Altered mental status
  • Skin and platelet dysfunction

STAGE 4:
SEPTIC
SHOCK

  • Diagnosed if there’s refractory hypotensions, and that IV fluid administration alone
    isn’t enough to maintain a patient’s blood pressure
  • Diagnosis of sepsis-induced hypotension is made when:
    • Systolic blood pressure (SBP) is < 90 mmHg
    • Mean arterial pressure (MAP) is < 70 mmHg, or
    • SBP decreases ≥ 40 mmHg without other causes for hypotension





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Sepsis 3.0: Implications for paramedics and prehospital care

Sepsis Early Recognition and Treatment in Prehospital Setting Vital for Patient Outcomes

Evidence Supports Using End-Tidal Carbon Dioxide to Detect Prehospital Sepsis

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DETECT SEPSIS WITH CAPNOGRAPHY

As we learn more about the symptoms of sepsis, clinicians recognize the importance of early detection and treatment, often starting in the prehospital environment. While lactate monitoring has traditionally been one of the most reliable ways to detect sepsis, these technologies are not always available in the field. Capnography’s quantitative waveform has proven to be a reliable way to detect respiratory failure and metabolic distress, allowing for early intervention and ongoing patient monitoring after treatment has been administered.


 

NON-INTUBATED
CAPNOLINES

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CAPNOLINES

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1 http://www.world-sepsis-day.org/CONTENTPIC/2015_WSD_FactSheet_long_English.pdf
2 http://www.g-i-n.net/conference/past-conferences/10th-conference/monday/2-45-pm-to-5-45-pm/lang-63.pdf
3 http://www.sepsis.org/faq
4 http://www.sepsis.org/downloads/2016_sepsis_facts_media.pdf
5 Condensed from http://www.jems.com/articles/print/volume-41/issue-9.html

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